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Progesterone Sleep Modulation

Meaning

Progesterone Sleep Modulation refers to the specific neuroendocrine action of the steroid hormone progesterone and its key metabolites, particularly allopregnanolone, in influencing sleep architecture and promoting sedation and anxiolysis. This modulation is a critical function of progesterone, often leveraged therapeutically to improve sleep quality, reduce sleep latency, and enhance the duration of non-REM sleep, especially in individuals with hormonal imbalances or sleep disturbances. The effect is mediated by direct interaction with neural receptors.