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Progesterone Requirement Stratification

Meaning

Progesterone Requirement Stratification is the clinical methodology of classifying an individual’s specific physiological need for progesterone or progestin therapy based on a comprehensive evaluation of their complete hormonal profile, specific clinical symptoms, and the nature of their concurrent hormone replacement regimen. Stratification determines the most appropriate dose, optimal route, and necessary duration of progesterone administration, moving beyond a standardized dose to a highly individualized therapeutic approach. This is particularly relevant in women receiving estrogen therapy and in men managing high estrogen conversion rates.