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Progesterone Estradiol Synthesis

Meaning

Progesterone Estradiol Synthesis describes the interconnected steroidogenic pathways primarily occurring in the gonads and placenta that result in the production of the two key female sex hormones, progesterone and estradiol. Progesterone is essential for preparing the endometrium for pregnancy and maintaining gestation, while estradiol, the most potent estrogen, regulates the menstrual cycle, bone density, and cardiovascular health. The synthesis of these hormones is tightly regulated by the Hypothalamic-Pituitary-Gonadal (HPG) axis and reflects the functional state of the reproductive system.