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Progesterone Cycling Efficacy

Meaning

Progesterone Cycling Efficacy refers to the measurable clinical success of administering progesterone in a pulsatile, cyclic pattern that accurately mimics the natural luteal phase of the healthy menstrual cycle, primarily in women with an intact uterus. This specific therapeutic strategy is absolutely crucial for protecting the endometrium from the proliferative effects of unopposed estrogenic stimulation, effectively managing common perimenopausal symptoms, and providing essential support for fertility. High efficacy is demonstrated by predictable withdrawal bleeding, profound and sustained symptom control, and the maintenance of optimal endometrial health and thickness. This approach underscores the non-negotiable importance of hormonal rhythm and sequence in female endocrine health.