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Progesterone Conversion Pathway

Meaning

The Progesterone Conversion Pathway describes the crucial sequence of enzymatic reactions by which the steroid hormone progesterone is metabolically transformed into other critical downstream steroid hormones and neurosteroids within various peripheral and central tissues. This pathway represents a central, indispensable branch of the overall steroidogenesis cascade, leading to the synthesis of mineralocorticoids, glucocorticoids, androgens, and neuroactive metabolites like allopregnanolone. It represents a key point of hormonal divergence and fine-tuned regulation in the entire body.