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Probiotic-Induced Dysbiosis

Meaning

Probiotic-induced dysbiosis is a paradoxical clinical phenomenon where the administration of certain probiotic strains or mixtures unintentionally disrupts the existing balance of the host’s gut microbiota, leading to an unfavorable microbial composition. Instead of restoring equilibrium, this intervention can sometimes result in symptoms like persistent bloating, abdominal discomfort, or an overgrowth of specific bacterial species in the small intestine. This adverse outcome highlights the complexity of the gut ecosystem and the need for personalized, evidence-based approaches to microbial supplementation. Careful selection of strain and dosage is critical to avoid iatrogenic imbalance.