Probiotic Benefits are the clinically demonstrated positive health effects resulting from the administration of adequate amounts of live microorganisms, typically specific strains of bacteria or yeast. These benefits often include improved digestive function, enhanced nutrient absorption, modulation of the immune system, and positive influence on the gut-brain axis. The specific benefits are strain-dependent and must be delivered at effective concentrations.
Origin
The concept of using beneficial microbes dates back to the early 20th century, but the modern clinical term “probiotic” was established to define the precise therapeutic use of these live organisms. This field has advanced significantly with the ability to genetically identify and clinically test specific strains for targeted health outcomes. It is a key intervention in the field of microbiome therapeutics.
Mechanism
Probiotics confer benefits through several mechanisms, including competitive exclusion of pathogenic bacteria, production of antimicrobial compounds, and direct interaction with the host’s immune cells in the gut. They can also aid in the breakdown of complex carbohydrates and the synthesis of essential vitamins, contributing to nutrient bioavailability. Specific strains are known to produce neurotransmitter precursors, thereby modulating the communication along the gut-brain axis.
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