A clinical philosophy centered on implementing interventions early in life or upon detection of early functional decline to slow the rate of biological aging across multiple systems, especially the endocrine network. This is not merely treating disease but actively preserving youthful physiological function to extend the duration of high-quality life. It requires anticipating age-related system failures.
Origin
This term is drawn from longevity research, emphasizing “proactive” measures taken before severe pathology manifests. It separates itself from reactive medicine by focusing on optimizing the fundamental drivers of aging, such as telomere attrition and cellular senescence, often through hormonal optimization.
Mechanism
The mechanism involves activating cellular maintenance and repair pathways before damage becomes irreparable or chronic inflammation sets in. This often includes maintaining optimal growth hormone/IGF-1 signaling balance and ensuring robust sex hormone support to preserve muscle mass and bone density. By sustaining cellular energetic efficiency and genomic stability through proactive means, the overall trajectory of functional decline is mitigated.
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