A strategic, individualized plan that projects an individual’s health trajectory over decades, utilizing predictive biomarkers and genetic data to implement preventative and performance-optimizing interventions well before the onset of symptomatic decline. This timeline shifts the clinical focus from reactive disease management to anticipatory wellness and longevity planning. It provides a structured framework for continuous, data-driven health optimization.
Origin
This term is a clinical-translational concept from the emerging field of personalized and preventative medicine, integrating the linear concept of a ‘timeline’ with the forward-looking strategy of ‘proactive health.’ It encourages a long-term view of biological aging.
Mechanism
The mechanism involves the longitudinal monitoring of key aging biomarkers, such as telomere length, epigenetic clocks, and systemic inflammation markers. Interventions are timed to prevent the critical inflection points of age-related decline, such as managing chronic metabolic load to prevent insulin resistance decades before diabetes onset. This strategy aims to compress morbidity and extend the period of high-grade vitality.
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