Proactive Anti-Aging Neurology is a preventative and restorative approach to neurological health that focuses on maintaining optimal cognitive function and mitigating age-related neurodegenerative risk factors long before clinical symptoms appear. It represents a shift from passive observation to active intervention in the aging of the central nervous system. The goal is to preserve and enhance the structural and functional integrity of the brain throughout the entire life course. This discipline recognizes the profound impact of systemic health on brain longevity.
Origin
This is an emerging field that blends gerontology, clinical neurology, and endocrinology, acknowledging the critical, bidirectional relationship between the endocrine system and brain health. It is rooted in the evidence that age-related cognitive decline is highly modifiable by managing systemic factors. The discipline applies a preventative lens to the well-established science of neuroplasticity and neuroprotection.
Mechanism
Interventions are strategically centered on promoting neurogenesis, which is the creation of new neurons, and enhancing synaptic plasticity, which is the brain’s ability to form new connections. This is accomplished by managing chronic neuroinflammation, optimizing cerebral blood flow, and ensuring optimal levels of key neurotrophic factors and neurosteroids. Maintaining youthful levels of hormones like DHEA and pregnenolone, which directly support neuronal integrity and function, is a key component of this mechanism.
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