A forward-looking, evidence-based clinical strategy focused on intervening early in life to modify physiological and molecular pathways before significant age-related decline manifests. This optimization utilizes advanced diagnostics and personalized protocols to maintain biological systems at a youthful set point, aiming to prevent the onset of chronic diseases and extend the period of peak vitality. It represents the ultimate goal of preventative longevity medicine.
Origin
This concept is a modern evolution of preventative medicine, moving beyond mere risk factor reduction to the active enhancement of biological function. It is heavily influenced by geroscience, which identifies aging as a modifiable process. The term emphasizes the strategic, preemptive nature of interventions, shifting the clinical focus from treating disease to cultivating health resilience.
Mechanism
The core mechanism involves precision modulation of key longevity pathways, including nutrient sensing, cellular senescence clearance, and epigenetic stability. By using targeted lifestyle, nutritional, and hormonal interventions, clinicians can influence gene expression and metabolic function to reduce the accumulation of molecular damage over time. This sustained systemic maintenance decelerates the rate of biological aging.
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