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Pro-Aging Pathway Inhibition

Meaning

Pro-Aging Pathway Inhibition is a therapeutic and lifestyle strategy aimed at actively suppressing specific molecular and cellular signaling cascades that are known to accelerate the biological processes of aging and cellular senescence. These pathways often involve nutrient sensing and stress response mechanisms, such as the mTOR, IGF-1, and NF-kB pathways, which, when chronically activated, can drive inflammation, protein aggregation, and cellular damage. The goal of inhibition is to extend the healthspan by promoting cellular repair, enhancing autophagy, and maintaining youthful tissue function. This is a central tenet of longevity medicine and preventative endocrinology.