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Primary Adrenal Deficiency Management

Meaning

Primary Adrenal Deficiency Management is the specific clinical protocol for treating Addison’s disease, a life-threatening condition characterized by the autoimmune or structural destruction of the adrenal cortex, resulting in inadequate production of cortisol and aldosterone. The management involves lifelong, precise physiological replacement of these glucocorticoid and mineralocorticoid hormones. The core objective is to mimic the body’s natural diurnal rhythm and stress-response capacity to prevent acute adrenal crisis while maintaining long-term quality of life and electrolyte balance.