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Premenopausal Fatigue

Meaning

Premenopausal Fatigue is a pervasive, often debilitating symptom of persistent exhaustion and lack of energy experienced by women during the years leading up to menopause, a phase known as perimenopause. This fatigue is frequently resistant to simple rest and is a common clinical complaint that is often rooted in the fluctuating and declining levels of key reproductive hormones, particularly estrogen and progesterone. The hormonal instability characteristic of this transition period profoundly impacts sleep quality, mood regulation, and thyroid function, contributing significantly to the overall sense of exhaustion.