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Pregnenolone Cognitive Precursor

Meaning

Pregnenolone Cognitive Precursor refers to the neurosteroid pregnenolone, which serves as the foundational precursor molecule for nearly all other steroid hormones, including cortisol, DHEA, testosterone, and estrogens, and is specifically recognized for its direct, non-hormonal modulatory role in cognitive function. Produced primarily in the adrenal glands and brain, pregnenolone acts as a potent neuromodulator in its own right, influencing receptor activity related to memory and learning. Its designation as a cognitive precursor highlights its dual role in systemic endocrinology and neuroprotection.