A state of excessive, sustained activation of the prefrontal cortex (PFC), the brain region responsible for executive functions such as planning, working memory, and complex decision-making. Chronic overstimulation, often due to multitasking, information overload, or perpetual stress, leads to reduced cognitive efficiency, impaired focus, and contributes significantly to mental fatigue. This state diminishes the PFC’s ability to effectively regulate emotional responses and maintain attention.
Origin
This term draws from cognitive neuroscience and the study of stress physiology, recognizing the finite capacity of the brain’s executive control system. It is a modern clinical concern linked to the demands of the hyper-connected, information-dense work environment. The concept is based on the neurobiological principle of neuronal resource depletion under sustained high load.
Mechanism
Sustained cognitive load demands a high metabolic rate in the PFC, leading to the rapid depletion of necessary neurotransmitters and energy substrates. The continuous need to process and filter vast amounts of information prevents the necessary periods of ‘default mode network’ rest and consolidation. Chronic stress, mediated by elevated cortisol, further impairs PFC function, reducing neuronal plasticity and making the brain less efficient at filtering irrelevant stimuli.
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