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Prefrontal Cortex Function

Meaning

Prefrontal Cortex Function refers to the executive cognitive domain governed by the anterior frontal lobe, encompassing complex processes such as working memory, inhibitory control, planning, and goal-directed behavior. Although a neurocognitive construct, this function is highly sensitive to modulation by systemic hormones, including glucocorticoids and sex steroids, which influence synaptic plasticity. Stable endocrine status is required for optimal PFC performance.