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Prefrontal Cortex Energy Stores

Meaning

Prefrontal Cortex Energy Stores refers to the readily available supply of metabolic substrates, primarily glucose and associated high-energy phosphate compounds like ATP, within the prefrontal cortex (PFC), the brain region responsible for executive functions such as working memory, decision-making, and attentional control. The PFC is metabolically demanding, and its energy status is highly sensitive to systemic factors like blood glucose stability and hormonal balance. Depletion of these stores leads directly to cognitive fatigue and impaired executive function.