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Prefrontal Cortex Androgens

Meaning

Prefrontal Cortex Androgens refers to the concentration and activity of male sex hormones, primarily testosterone and its metabolites like dihydrotestosterone (DHT), within the prefrontal cortex region of the brain. This area is critically responsible for executive functions, including decision-making, working memory, and impulse control. These hormones act as potent neuro-modulators, influencing neuronal excitability, synaptic plasticity, and the expression of neurotransmitter receptors. Optimal levels are essential for maintaining cognitive sharpness and emotional regulation, particularly in the aging male and female brain.