Question 1

What is the Meaning of Precision Molecular Medicine?

Accepted Answer

Precision Molecular Medicine is an advanced, mechanistic clinical paradigm that leverages an individual's unique, high-resolution molecular and cellular data, encompassing genomic, proteomic, and metabolomic profiles, to customize all diagnostic and therapeutic strategies. This approach rejects the conventional one-size-fits-all model by identifying the specific molecular targets and pathway dysregulations that are driving an individual's health trajectory or disease risk. The ultimate goal is to ensure the right intervention is delivered to the right patient at the right time.

Question 2

What is the Origin of Precision Molecular Medicine?

Accepted Answer

This discipline emerged from the technological revolution following the Human Genome Project, which made large-scale, individualized molecular data acquisition both feasible and clinically interpretable. It represents the natural evolution of medicine, integrating detailed, upstream biological information into the core of clinical decision-making and personalized health management.

Question 3

What is the Mechanism of Precision Molecular Medicine?

Accepted Answer

The mechanism involves comprehensive molecular profiling to detect subtle, functional variations in enzyme kinetics, receptor density, and gene-hormone interaction patterns that dictate an individual's unique phenotype. For example, in hormonal health, it identifies genetic polymorphisms affecting hormone metabolism or receptor binding, allowing for the precise selection and dosing of specific hormone analogs or modulators. The function is to establish a molecular-level diagnosis, enabling the design of interventions that precisely correct the identified, root-cause molecular dysregulation.

Precision Molecular Medicine

Meaning

Origin

Mechanism

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