A specialized, evidence-based medical discipline that utilizes advanced diagnostics, personalized data, and targeted interventions to optimize physiological function, prevent age-related diseases, and extend the period of robust health (healthspan). This approach integrates endocrinology, genetics, and molecular biology to create highly individualized protocols. It aims to treat the root mechanisms of biological aging rather than merely managing disease symptoms.
Origin
This term represents the evolution of anti-aging medicine, shifting the focus from general wellness to scientifically rigorous, data-driven, and mechanism-based interventions. The precision element is borrowed from oncology and genetics, emphasizing the use of high-resolution biological data to tailor therapies to an individual’s unique molecular profile. It is the clinical manifestation of geroscience research.
Mechanism
Precision Longevity Medicine operates by identifying and modulating the nine hallmarks of aging, including genomic instability, telomere attrition, and mitochondrial dysfunction. Key mechanisms involve the personalized optimization of the endocrine system, targeted supplementation to activate longevity pathways like AMPK and sirtuins, and the use of senolytics to clear senescent cells. The entire process is driven by continuous monitoring of biological age biomarkers and functional metrics.
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