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Precision Intervention Thresholds

Meaning

Precision Intervention Thresholds are highly specific, evidence-based numerical values for biomarkers or physiological parameters that, when crossed, necessitate the initiation or intensification of a targeted therapeutic intervention. Unlike broad clinical guidelines, these thresholds are often personalized, taking into account the patient’s unique genetic profile, existing subclinical disease burden, and overall hormonal and metabolic status. These thresholds define the point at which the quantifiable risk outweighs the risk of intervention, guiding a proactive and precise clinical strategy.