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Precise Dosing Chronology

Meaning

Precise Dosing Chronology is a clinical methodology focused on administering pharmaceutical or nutraceutical agents at specific, optimized times of the day to align with the body’s natural circadian rhythms and maximize therapeutic efficacy while minimizing side effects. This strategy acknowledges that the body’s physiological responses, hormone secretion patterns, and receptor sensitivities vary predictably over a 24-hour cycle. In hormonal health, this means timing hormone replacement or regulatory agents to mimic the body’s endogenous pulsatile release patterns, ensuring superior biological uptake and utilization. This personalized approach moves beyond fixed dosing schedules to leverage chronopharmacology.