Prebiotic foods are dietary components, primarily non-digestible fibers and oligosaccharides, that selectively stimulate the growth and activity of beneficial bacteria residing in the colon. These specific food substances are crucial for fostering a healthy gut microbiome, which in turn influences systemic health, including immune function and endocrine signaling. Integrating prebiotic-rich foods into the diet is a key strategy for supporting gut health and potentially modulating the gut-brain axis and overall metabolic balance.
Origin
The term prebiotic was coined in the mid-1990s, distinguishing these dietary ingredients from probiotics (the live microorganisms themselves). The word structure, pre- (before) and biotic (life), emphasizes that these substances are the necessary nourishment before the beneficial microbial life can flourish.
Mechanism
Prebiotic fibers pass undigested through the upper gastrointestinal tract until they reach the large intestine, where they are selectively fermented by commensal bacteria, such as Bifidobacteria and Lactobacilli. This fermentation process produces beneficial short-chain fatty acids (SCFAs), including butyrate, propionate, and acetate, which serve as energy sources for colonocytes and exert systemic effects, including improved insulin sensitivity and anti-inflammatory signaling.
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