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Prasterone

Meaning

Prasterone is the pharmaceutical term for the endogenous steroid hormone Dehydroepiandrosterone, or DHEA, a prohormone secreted primarily by the adrenal glands. It serves as a crucial precursor for the biosynthesis of both androgens, like testosterone, and estrogens, like estradiol, making it a foundational component of the body’s steroidogenic cascade. Clinically, Prasterone is used in specific formulations to address conditions related to DHEA deficiency, such as vulvovaginal atrophy in postmenopausal women or to support overall hormonal balance. Its appropriate use requires careful monitoring of downstream hormone metabolites.