PQQ Supplementation refers to the clinical or wellness practice of orally administering Pyrroloquinoline Quinone, a potent redox cofactor, to support cellular health, particularly mitochondrial biogenesis and function. PQQ is recognized for its antioxidant properties and its unique ability to promote the formation of new mitochondria within cells. This practice is aimed at enhancing cellular energy production and overall vitality.
Origin
This term stems from nutritional biochemistry and mitochondrial research, following the identification of PQQ as a novel vitamin-like compound with significant biological activity. “Supplementation” denotes its use as an exogenous compound to enhance physiological processes.
Mechanism
PQQ acts by activating signaling pathways, most notably the CREB and PGC-1alpha pathways, which are master regulators of mitochondrial biogenesis. Furthermore, its robust antioxidant capacity allows it to scavenge reactive oxygen species within the mitochondria, protecting the integrity of the cellular powerhouses and ensuring sustained, efficient ATP production.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.