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PPRS

Meaning

PPRS, in the context of cardiovascular endocrinology, is an acronym for the Plasma Prorenin Receptor System, which is a critical component of the Renin-Angiotensin-Aldosterone System (RAAS) that regulates blood pressure and fluid balance. This system involves the binding of prorenin or renin to the specific Prorenin Receptor, leading to non-catalytic activation of angiotensinogen conversion and downstream effects on tissue remodeling. Dysfunction in the PPRS is implicated in hypertension, cardiac fibrosis, and other cardiovascular diseases.