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Postprandial Fullness

Meaning

Postprandial Fullness, clinically referred to as satiety, is the physiological sensation of comfortable repletion and cessation of hunger that follows the ingestion of a meal, marking the termination of the eating episode. This sensation is a complex, integrated signal resulting from the mechanical distension of the stomach, the chemosensory detection of nutrients, and the coordinated release of multiple gut-derived satiety hormones. It is a critical component of energy balance and body weight regulation, directly influenced by gastrointestinal and endocrine function.