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Postoperative Hormonal Suppression

Meaning

Postoperative hormonal suppression is a clinical strategy involving the deliberate administration of medications following surgery to reduce or eliminate the production or action of specific endogenous hormones. This intervention is frequently employed in the management of hormone-sensitive conditions, such as endometriosis or certain cancers, to minimize the risk of disease recurrence or progression. The goal is to create a hypoestrogenic or hypoandrogenic environment to inhibit the proliferation of residual hormone-dependent cells. This specialized approach requires careful endocrine monitoring and patient education regarding potential side effects.