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Postmenopausal Cognitive Resilience

Meaning

Postmenopausal Cognitive Resilience is the sustained capacity of the brain to maintain high-level cognitive function, including memory, processing speed, and executive function, despite the profound and permanent decline in ovarian hormone production following menopause. This concept focuses on the protective biological and lifestyle factors that enable certain women to resist the common neurocognitive decline associated with chronic estrogen withdrawal. Clinically, fostering this resilience is a key goal in hormonal health and longevity, involving strategies to support neuroplasticity and minimize neuroinflammation and metabolic stress.