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Post-TRT Recovery Trajectory

Meaning

Post-TRT Recovery Trajectory is the chronological and biochemical course of the Hypothalamic-Pituitary-Gonadal (HPG) axis as it attempts to restore endogenous testosterone production following the cessation of exogenous Testosterone Replacement Therapy (TRT). This trajectory is a critical clinical assessment that tracks the recovery of Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), and endogenous testosterone levels over weeks to months. The steepness and completeness of this recovery are highly variable and influenced by the duration of TRT, the specific TRT agent used, and the recovery protocol employed.