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Post-Injection Discomfort

Meaning

Post-injection discomfort refers to the localized, often transient, sensation of pain, soreness, or irritation experienced at the site where a subcutaneous or intramuscular injection was administered. This common side effect can range from mild tenderness to significant local inflammation, impacting patient adherence to chronic injectable therapies, such as hormone replacement or peptide treatments. The severity is influenced by the injection technique, the volume, and the physicochemical properties of the formulation.