Skip to main content

Platelet Aggregation

Meaning

Platelet aggregation is the physiological process by which platelets, small, anucleated blood cells, adhere to one another at the site of vascular injury to form a hemostatic plug, initiating the cascade of blood clot formation. This rapid, localized response is essential for preventing hemorrhage and maintaining circulatory integrity. In the context of hormonal health, the balance of this process is clinically relevant because sex hormones, particularly estrogen, can modulate platelet activity and coagulation factors, thereby influencing the risk of thrombotic events.