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PKC Signaling Augmentation

Meaning

PKC Signaling Augmentation describes the clinical strategy of enhancing the activity of Protein Kinase C (PKC), a family of enzymes that plays a pivotal role in intracellular signal transduction for a wide array of cellular functions, including hormone response, neurotransmitter release, and gene expression. Targeted augmentation aims to restore optimal cellular communication, particularly in systems where hormonal or neural sensitivity has diminished with age or pathology. This is a nuanced approach to cellular optimization.