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Pituitary Gonadotropin Output

Meaning

Pituitary Gonadotropin Output refers to the pulsatile secretion of the glycoprotein hormones Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) from the anterior pituitary gland, which are the primary signals regulating gonadal function in both males and females. This output is directly controlled by the Hypothalamic-Pituitary-Gonadal (HPG) axis, specifically by the release of Gonadotropin-Releasing Hormone (GnRH) from the hypothalamus. Measuring the output provides a direct clinical assessment of the central drive for sex hormone production and is essential for diagnosing conditions related to reproductive and endocrine aging.