Refers to the body of scientific investigation dedicated to elucidating the biological actions, clinical efficacy, and underlying mechanisms of the peptide Pinealon, a synthesized short-chain peptide derived from the bovine pineal gland. The research primarily explores its potential role in regulating pineal function, promoting restorative sleep, and influencing endocrine signaling, particularly the production of melatonin. It is studied for its geroprotective effects.
Origin
Pinealon is one of the foundational Russian bioregulator peptides developed by the Khavinson group, emerging from decades of gerontological research focused on restoring tissue-specific function using targeted peptide therapy. The research is rooted in experimental endocrinology and the concept of peptide-based biological regulation. This work established a new class of regulatory compounds.
Mechanism
The peptide is hypothesized to function by interacting with specific gene sequences in the pineal gland, promoting the transcription and translation of proteins necessary for normal cellular function and hormone synthesis. By restoring the optimal function of the pineal gland, Pinealon is believed to help normalize the circadian rhythm. This enhancement supports the systemic signaling of the neuroendocrine system.
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