The targeted therapeutic application of the synthetic peptide Pinealon, a tripeptide derived from the pineal gland, to modulate and restore the endogenous function of the pineal gland and the associated neuroendocrine system. This process is clinically aimed at normalizing the circadian rhythm, enhancing antioxidant defense, and supporting overall brain and immune function, particularly as it declines with age. It is a form of peptide-based bioregulatory therapy.
Origin
This term stems from the field of peptide bioregulation, pioneered by Russian scientists, which focuses on using short, tissue-specific peptides to restore the function of the organ from which they were originally derived. Pinealon’s origin is directly linked to the pineal gland, the source of melatonin, and its application is based on decades of preclinical and clinical research in this specific area.
Mechanism
Pinealon is believed to act by interacting with specific nuclear receptors or gene promoters within pinealocytes, the primary cells of the pineal gland, to modulate the transcription and translation of regulatory proteins. This action leads to the restoration of endogenous melatonin synthesis and secretion patterns, thereby re-synchronizing the body’s circadian rhythms. Furthermore, its influence extends to the immune system, where it helps regulate T-cell function and cytokine production.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.