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PhysiologicalResilience

Meaning

Physiological Resilience is the measurable capacity of a biological system—from the cellular level to the entire organism—to rapidly adapt, recover, and maintain homeostatic equilibrium when exposed to internal or external stressors, such as illness, psychological strain, or intense physical exertion. This robust state is underpinned by optimal hormonal axis function, a strong immune response, and efficient metabolic flexibility. Clinically, enhancing resilience is a core goal of longevity medicine, as it determines the individual’s ability to resist chronic disease and functional decline over time. It represents the adaptive strength of the body.