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Physiological Window Targeting

Meaning

The precise clinical strategy of administering a therapeutic agent, such as a hormone or peptide, at a specific time point or in a specific concentration range to maximize its intended biological effect while minimizing adverse outcomes. This approach recognizes that the responsiveness of target tissues to a signal is not constant but varies based on the body’s circadian rhythms, metabolic state, and the presence of other co-regulatory signals. It is the art and science of timing a treatment for optimal systemic integration.