Skip to main content

Physiological Stress Mitigation

Meaning

Physiological Stress Mitigation is the systematic implementation of therapeutic and lifestyle strategies designed to reduce the allostatic load and suppress the chronic, detrimental effects of excessive sympathetic nervous system and hypothalamic-pituitary-adrenal (HPA) axis activation. This intervention aims to restore a state of neuroendocrine balance by lowering chronically elevated levels of cortisol and adrenaline, which are potent drivers of metabolic dysfunction, immune suppression, and accelerated aging. Clinically, successful mitigation is measured by a reduction in objective biomarkers of stress and a profound improvement in subjective well-being and recovery capacity. It is an essential precursor to effective hormonal optimization.