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Physiological Reserve

Meaning

Physiological reserve is the quantifiable capacity of an organ or system to function at a level significantly higher than the demands of normal, resting conditions, providing a buffer against stressors, injury, or disease. This reserve capacity is a critical determinant of resilience and is largely dependent on the functional integrity of key systems, including the cardiovascular, pulmonary, and endocrine axes. A diminished reserve is a hallmark of advanced aging and increases vulnerability to decompensation.