What is the Origin of Physiological Re-Sequencing?

The term draws upon the scientific fields of chronobiology and systems physiology, where the body's functions are recognized as operating on predictable, time-dependent sequences. "Re-Sequencing" is a therapeutic concept, implying that the natural, genetically encoded order of these biological events can be intentionally restored through targeted, time-specific interventions.

What is the Mechanism of Physiological Re-Sequencing?

Re-sequencing protocols typically involve light therapy to modulate the central pacemaker in the brain, the suprachiasmatic nucleus (SCN), alongside the strategic timing of meals, exercise, and chronotherapeutic administration of specific hormones or nutrients. By correcting the timing of these external and internal inputs, the central pacemaker is recalibrated, which subsequently re-establishes the proper sequence of downstream hormonal and metabolic events, such as the nightly cortisol nadir and the timely melatonin peak.

Physiological Re-Sequencing ∞ Area

Physiological Re-Sequencing

Meaning

Physiological Re-Sequencing is a clinical paradigm that involves the systematic and hierarchical restructuring of biological processes that have become dysregulated due to chronic stress, aging, or underlying pathology. This therapeutic strategy aims to restore the natural, optimal timing and coordination of key physiological cycles, such as the circadian rhythm, the sleep-wake cycle, and the rhythmic, pulsatile release of hormones. The clinical objective is to reset the body’s internal biological clock, known as the chronome, for enhanced health, metabolic efficiency, and longevity.