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Physiological Pulsatile Secretion

Meaning

Physiological Pulsatile Secretion describes the characteristic, intermittent, burst-like release pattern of many crucial hormones, particularly those involved in the hypothalamic-pituitary axes, as opposed to a continuous, steady flow into the circulation. This rhythmic, non-continuous pattern of secretion is not random but is tightly regulated by central oscillators and is absolutely crucial for maintaining the sensitivity of target tissue receptors and ensuring the proper, full downstream biological effect. The specific frequency and amplitude of these secretory pulses convey essential regulatory information to the target glands and tissues.