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Physiological Impairment

Meaning

Physiological Impairment describes a measurable reduction or defect in the normal function of an organ, system, or biological process, indicating a deviation from the state of optimal health or homeostasis. In the hormonal context, this could manifest as reduced glandular output, impaired hormone receptor sensitivity, or inefficient metabolic clearance of steroid hormones. Identifying and quantifying this impairment is the primary goal of advanced clinical diagnostics, as it represents the functional consequence of underlying disease or chronic systemic stress.