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Physiological Dosing Range

Meaning

The Physiological Dosing Range defines the concentration of an exogenous substance, such as a hormone or nutrient, administered to replicate the levels naturally produced by a healthy, optimally functioning endogenous system. This clinical principle ensures that interventions restore hormonal balance without inducing supraphysiological effects or suppressing the body’s native production mechanisms. Doses within this range are designed to elicit the beneficial effects of the molecule while minimizing the risk of adverse side effects or disruption of the homeostatic setpoint.