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Physiological Dose Titration

Meaning

Physiological Dose Titration is the precise clinical process of incrementally adjusting the dosage of a therapeutic agent, typically a hormone or essential nutrient, to achieve and maintain a concentration that closely mimics the natural, healthy levels found in a young adult. The goal is to restore endogenous signaling patterns without causing pharmacological excess or inducing negative feedback loops that suppress the body’s own production. This meticulous, individualized dosing strategy is guided by continuous objective biomarker monitoring and subjective symptom reporting, ensuring maximal therapeutic benefit with minimal risk.