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Physiological Constraints

Meaning

Physiological constraints are the inherent biological limitations, defined by an individual’s current genetic makeup, age, pathology, or environmental circumstances, that restrict the range of possible adaptive responses and therapeutic outcomes. These constraints represent the biological “speed limits” of the human system, dictating the maximum rate of healing, the achievable degree of hormonal optimization, or the tolerance for therapeutic intervention. Recognizing these limitations is essential for setting realistic clinical expectations and preventing iatrogenic harm.