What is the Origin of Physiological Communication Integrity?

This is a broad concept rooted in general systems physiology, emphasizing the necessity for uninterrupted signal transduction across the entire hierarchy of the body's regulatory apparatus. It demands viewing the body as a single, integrated communication entity rather than separate functional axes.

What is the Mechanism of Physiological Communication Integrity?

Integrity relies fundamentally on the correct synthesis, efficient transport through the circulatory system, appropriate receptor affinity at the target site, and timely degradation of all signaling molecules. Any impairment, such as inflammatory degradation of receptor function or decoupling of metabolic signals, compromises this foundational organizational coherence.

Physiological Communication Integrity ∞ Area

Physiological Communication Integrity

Meaning

Physiological Communication Integrity is the optimal state where all essential regulatory signaling pathways, encompassing endocrine, paracrine, and autocrine mechanisms, transmit information accurately and without pathological interference across all organ systems. This ensures the body’s intricate network of chemical messengers functions cohesively to maintain dynamic homeostatic equilibrium. Preserving this integrity is synonymous with robust systemic health.