What is the Origin of Physiological Cohesion?

This is a descriptive term, combining 'physiological' (relating to the function of the body) and 'cohesion' (the act of sticking together or unity). The concept underscores the systems biology view of the human body, recognizing that no single system operates in isolation. Its clinical utility lies in shifting diagnostic focus from isolated symptoms to patterns of systemic communication failure.

What is the Mechanism of Physiological Cohesion?

The mechanism is mediated by complex feedback loops and shared signaling molecules, particularly hormones and cytokines. For example, cortisol, an endocrine product, modulates immune cell activity and neurotransmitter release, illustrating a direct link between the three systems. High cohesion means that the stress response initiated by the nervous system is appropriately moderated by the endocrine system and does not result in a maladaptive immune response, ensuring systemic stability and optimal performance.

Physiological Cohesion ∞ Area

Physiological Cohesion

Meaning

Physiological Cohesion refers to the harmonious, synchronized operation and interdependence of the body’s major regulatory systems, including the endocrine, nervous, and immune systems. This state is characterized by robust inter-system communication, allowing for rapid and appropriate adaptation to internal and external stressors, which is fundamental to maintaining health and resilience. Loss of cohesion, often seen in chronic disease, manifests as systemic dysregulation.