Skip to main content

Physiological Activation

Meaning

Physiological activation denotes the precise process by which a specific endogenous signal or an exogenous stimulus successfully initiates a targeted, measurable biological response within a specific tissue, an organ system, or an entire systemic network. In the context of hormonal health, this term accurately describes the functional consequence of a hormone successfully binding to its cognate receptor, leading to a cascade of subsequent cellular events that fundamentally alter the body’s state, such as the metabolic activation of the thyroid gland by TSH. It represents the foundational principle of all biological responsiveness and functional change.